Project - Codeine-6-Glucuronide (C6G)

[monstanoodle]

With the help and suggestion of sixpartseven I've gone ahead and made a new page with the request of somebody creating a page on the "official" Wiki on Codeine-6-Glucuronide (C6G) - the main metabolite of Codeine now thought to be responsible for the majority of it's Analgesic and potentially Euphoric action

If anyone who has a clue how to edit / create pages on Wiki (I tried and failed massively) would be up for this it'd be really, really grand

The info I've managed to find on C6G is as follows:
Codeine analgesia is due to codeine-6-glucuronide, not morphine.
Details of Chemical names and a diagram of it's chemical structure.
Analgesic effects of codeine-6-glucuronide after intravenous administration
Metabolism process of Codeine.

Again, thankyou muchly if somebody chooses to go ahead with this, and no worries if not as I can imagine it being a bit of a task

[sixpartseven]

Awesome job on getting the ball rolling. Just so you know, we're getting things together still, so it might be a slow going getting this project finished for the time being. We really appreciate you utilizing the forum and starting a project though. Hang in there - give people time to check out the forum and get involved - and soon enough, you'll see your idea come to life, living on our Wiki.

[monstanoodle]

Time isn't as precious a commodity as info so all be well in that respect
Nice to know this will go forth Cheers 6/7!

[adder]

It is a bit of a task as various papers don't agree with themselves on this topic.

[Provoke]

What yields for each conversion in your pdf file? Would be nice to have em. I heard it converts into morphine with 10% rate.

[monstanoodle]

Wiki gives a good chunk of metabolism ratio:

Roughly 5-10% of codeine will be converted to morphine, with the remainder either free, conjugated to form codeine-6-glucuronide (~70% ), or converted to norcodeine (~10% ) and hydromorphone (~1% ).

Seeing as it's a good 70% or so, there must be atleast some effect. Compared to Morphine, I (used to ) get so much more from an equivalent dose of Codeine.