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Archive - OD>Naltrexone: ULD to stop tolerance buildup and Precipitated Withdrawals
CretiNation 18:49 20-02-2008
Ok guys! I just made a solution of 0.001mg/ml (1 mcg/ml) naltrexone hcl and plan on trying it (I'm thinking 1ml - any feedback??) with about $10 of NE #4 once I get home from work. This isn't any sort of controlled or measured experiment in anyway, I just wanna satisfy my curiosity about the acute effects (if any) of this combination. Tick tick tock!
Nik Dynosaur 19:05 20-02-2008
Wasn't negrogesic toying with this a couple years or so back? I think he may have posted a thread about it, i'm going to try and find it.
Spaazkaz 19:57 20-02-2008
I dont mean to pick but your denial of your addiction is way more serious than trying to detox.

"So I have come across 3 x Naltrexone HCl 50mg pills (Imprint: b / 50 over 902).

I was initially interested in these for precipitated withdrawals. Recently I've been doing heroin and, while I haven't done enough to really serious physical addiction or to get serious withdrawal symptoms (I get blasted off $20 still), I have been dosing daily for quite some time."

been dosing daily for quite some time...
trying to detox w/ chemical help...
2 bags a day isn't a "serious" addiction but its an addiction nonetheless.
think about it... you are using every day how can you not be addicted?

Im really not trying to start a ruckus here but this bothers the shit out of me.

be e z, -Spaz-
TheodoreRoosevelt 21:12 20-02-2008
Originally Posted by :
Im really not trying to start a ruckus here but this bothers the shit out of me.
Great, here's my carecup \_/

Even if I had an addiction so what, all your post does is derail the thread. So let's assume you are correct, that I am physically addicted: You still fail to answer two inquiries I posted about: ULD Dosing and Naltrexone as a detoxification agent in a person who has levels of heroin present in their body that do not amount to physical addiction levels

If you read anything at all, you would have seen the answers to your questions. I have Chronic insomnia, which means it's persistent. Most forms of insomnia last for a few days to a couple months. I've had insomnia for over 10 years now. Last year, I could count the number of days I slept before 4 AM on my hand. The fact of the matter is that without the use of drugs, I cannot fall asleep unless I have been up for over 20 hours.

Due to this extreme chronic insomnia and my RLS, which have been medically diagnosed and on my medical records, I am resilient to heroin withdrawal symptoms. Any kind of withdrawal symptoms I may have been subject to, I simply don't notice because I already have the most major symptoms of acute withdrawal - insomnia and RLS. In a way, I'm always in withdrawal.

Am I psychologically addicted? I believe I am, to a severe degree. But I am not physically addicted. It is not denial, it is the truth, as I have quit heroin once again and have yet to feel any withdrawal symptoms. Sorry to dissapoint you.

ANYWAYS:


When you use heroin just once, you will have some in your system. The idea by many is that you can use heroin 3 days, but you must give your system a 3 day, or whatever, break before you can use again to avoid addiction for most people. My theory is that you could use naltrexone to detoxify your system quicker, and make this break period shorter.

Detox doesn't just refer to clearing out a high level addiction, it just means cleaning out your system. You can detox your body even if you have no drug addiction. It is simply a way to purify your body of whatever, there are many kinds of detox. The detox I am referring ot here, is in reference to the fact that even if you do one bag of heroin, your only one that month, you will have heroin in your system. I was wondering how to detox low amounts of heroin in the body with naltrexone.

Obviously, there is a point in your drug use where you would not get withdrawal symptoms, and a point where you would. If you continue to use, you will get to have withdrawal symptoms and enter that stage of addiction. At this point, you need to take a short break from heroin, so you can return your body to baseline, and start afresh - in other words, you need to detox before you can continue using without getting a physical addiction. I was thinking you could use naltrexone to speed up this detoxification, and shorten this break.

We all have heard that regarding heroin use, it is "3 days on, 3 days off". I was thinking with the aide of naltrexone, you could shorten the time "off". Ie, make it 3 days on, 1 day off w/naltrexone". My question is what dose of naltrexone would you take, how you administer it, and how long does the naltrexone last in your system.


Originally Posted by :
Ok guys! I just made a solution of 0.001mg/ml (1 mcg/ml) naltrexone hcl and plan on trying it (I'm thinking 1ml - any feedback??) with about $10 of NE #4 once I get home from work. This isn't any sort of controlled or measured experiment in anyway, I just wanna satisfy my curiosity about the acute effects (if any) of this combination. Tick tick tock!
Good luck! If this turns out to be too much, you won't get high. Make sure you try it with some dope you've done before, so you can tell if you either just got weak dope, or if the naltrexone itself actually interfered with the high. There are reports that using naltrexone in ULD can actually incrrease the high, so that's another reason you should be familiar with the dope, that way you can tell if it's potentiated by the antagonist. In any event, if it doesn't weaken your high, it should at least help in preventing tolerance buildup.

Please report!
Spaazkaz 22:33 20-02-2008
While it may be wrong of me, It was of my opinion to bring to your attention a topic that i thought was more important and does loosely relate to your post.

You just expect me to have read your threads? what?! you are mad because i don't know you background because i haven't read, don't remember your threads? thats not right...

I appreciate you being so thorough in your explanation of your history. I thought by you using daily 2-4 shots a day for quite some time you meant that you had not stopped since you started. I thought you hadn't gone through withdrawals and had no idea what you were going against. i didn't realize you have withdrawn after binges with no ill effects. I also didn't realize you admit to being psychologically addicted. Man, I was simply looking out for a fellow bluelgihter, i meant no harm by it. I am an addict and try to care for addicts around me. It helps me to come on this board everyday to help people. i truly apologize if i stirred your pot (in the bad way).

I'm sorry i don't know the answer to your OP and in retrospect i should have just pm'd you.

Sorry, -Spaz-
Spaazkaz 22:39 20-02-2008
Theodore and I have come to an understanding via PM. The score has been settled. -Spaz-
TheodoreRoosevelt 22:42 20-02-2008
Originally Posted by :
I thought by you using daily 2-4 shots a day for quite some time you meant that you had not stopped since you started. I
Oh no, it's 2-4 weeks, shooting only a medium dose per day, only once the day, and at night, at the end of the day. Jesus, 4 shots a day, I could not imagine that.

Originally Posted by :
I thought you hadn't gone through withdrawals and had no idea what you were going against. i
I've never gone through noticeable withdrawal and I've gone as far to use daily for as long as 5 weeks (with a couple days of breaks here in there for whatever obligations). I just take longer to develop them I guess. I may have felt minor symptoms before, ie a little chilly or the shits, but nothing really significant and that couldnt have been from something else or merely placebo. Definitely never significant symptoms though. I'm sure I've gone through withdrawal, but never noticed simply because of my severe insomnia.

For the longest time I thought withdrawal took like 3 months of daily use to develop, and despite using heroin for over 4 years, I just learned like 2 months ago that it takes only like 3 days for most people to start to take root.

I can see how you got misled, sorry to be hostile (man I'm an ass sometimes). I should've been more clear and wasn't, I didn't really want to explain it all again since I'm sure most people are sick of hearing over and over how I never get addicted. I appreciate you taking the time to reconcile and sorry for being such an ass. It's at least partially my fault for not being more clear. Most people know how I've chipped so I shouldn't have assumed you would have too.

Anyways, back on topic!

Originally Posted by :
Obviously, there is a point in your drug use where you would not get withdrawal symptoms, and a point where you would. If you continue to use, you will get to have withdrawal symptoms and enter that stage of addiction. At this point, you need to take a short break from heroin, so you can return your body to baseline, and start afresh - in other words, you need to detox before you can continue using without getting a physical addiction. I was thinking you could use naltrexone to speed up this detoxification, and shorten this break.

We all have heard that regarding heroin use, it is "3 days on, 3 days off". I was thinking with the aide of naltrexone, you could shorten the time "off". Ie, make it 3 days on, 1 day off w/naltrexone". My question is what dose of naltrexone would you take, how you administer it, and how long does the naltrexone last in your system.
And CretiNation please report how it goes!
TheodoreRoosevelt 10:48 21-02-2008
Up.

Can anyone answer how naltrexone can be used for someone who has little or not tolerance?

Any insight on how naltrexone could be used to make the "3 days on 3 days off" break shorter? How would it feel? What dose would you use?

I mean what would happen if YOU used naltrexone? Just any insight on using naltrexone to bring precipitous, um, detox, would be nice.
Ham-milton 20:51 21-02-2008
1mcg/ml is insanely low.
TheodoreRoosevelt 13:28 29-03-2008
Well I haven't done any dope in a day or so and I'm getting kinda sleepy, so I swallowed 2 x 3mg Melatonin pills to knock my ass out, hopefully, and ate like, uhh, like a roughyl split third of a half of a 50mg Naltrexone pill, so like 6-8mg of Naltrexone.

I dunno what it's gonna do. Here's to finding out.
wiggi 15:30 29-03-2008
^ Welcome to withdrawals. Good luck.
TheodoreRoosevelt 15:52 29-03-2008
I took too much melatonin
wiggi 16:01 29-03-2008
Try taking a hot bath. That always seemed to help me.
TheodoreRoosevelt 17:40 29-03-2008
do not take too much melatonin
wiggi 17:47 29-03-2008
I don't think you should call 911. Just sounds like you are going into precipitated withdrawals. I know exactly how you feel, I woke up in the hospital after receiving a shot of narcan. I'm sure you can hang it out. But, I'm not a doctor, it's your call.
smackem 03:23 30-03-2008
What we are saying is: Why are you interested in 'detoxing with naltrexone' if you arn't physically addicted? If you arn't physically addict, like you say, you would have no withdrawls to precipitate. But, I think you are a bit addicted so, I think it would precipitate SOME wds. other people have tried this ULD stuff, searchfor the threads. One guy made a journel.


Oohhh wait, you DID take that pill. and you did get precipitated withdrawls, whaddya know :-). Well, it should go away in like 12 hours. Just keep some dope for then. Or you can shoot dope over the antagonist, but they say its dangourus.


Why did you take that pill again? Did you want to precipiate withdrawls or not? I guess you wanted too :-). I hope at least.

Don't call 911, just man it out.
negrogesic 03:43 30-03-2008
Yes, im not 100% why you took it to begin with, maybe i didnt read thoroughly enough...
TheodoreRoosevelt 04:34 30-03-2008
Hm, well here's the story.

I've been doing about $10-20 of dope daily or so for about 2 months. For whatever reason, physical addiction seems to develop slower in me and I'm not as privy to the effects since I have pretty extreme insomnia and RLS (both medically diagnosed. To give an example, my freshmen year I never went to bed before 4am).

Last night I took about 10mg of Naltrexone orally when I was pretty tired, thinking I could maybe detox my system a bit while I slept. I also took 6 x 3mg = 18mg Melatonin to help me sleep, as I always have a hard time getting to sleep.

The pain I was ranting about earlier in this thread came from eating WAYYYY too much Melatonin, I believe you aren't supposed to go past 9mg in a 24 hour period.

I'm pretty sure I wasn't going through withdrawal (or maybe partially I was, whatever), but that this pain was from eating too many sleeping supplements. At one point I was outside crawling, puking my guts out, in a fetal position outside. My stomach still hurts but whatever.

Thanks wiggi for your posts, I know I felt the withdrawal come on but that wasn't nearly as bad as the pain I felt from taking too much melatonin.

Originally Posted by :
ngesting melatonin supplements may cause some unwanted side effects, especially at high doses (~more than 3 mg/day)

wiggi 04:52 30-03-2008
^^ No problem Teddy, glad you're ok and figured out what happened.
negrogesic 05:32 30-03-2008
Yes, as you mentioned, it can be extremely uncomfortable taking large amounts of melatonin, very unpleasant at best. There is alot of physical pain from high doses of melatonin, a strange burning sensation that can be frightening (i once made the huge mistake of taking 12mg of melatonin while on LSD, dont ask me why). Though very different, i can see how you could have mistaken this for drug withdrawal.

Also, perhaps im still unclear, but are you still taking heroin?
CretiNation 20:41 12-04-2008
Theo: it sounds to me like you ran into a terrible case of precipitated WD. Maybe you also took too much of the supplement but nausea, vomiting, GI discomfort etc are hallmark WD symptoms and do not happen with excess melatonin.

Anyway, the past 7 days I have been doing ULD naltrexone with each shot of heroin. I have also gotten 3 of my friends (also daily users) to do the same. I'm still experimenting with dosing but so far I (as well as my 3 friends) have had INCREDIBLY SUCCESSFUL results with using ~1-2mcg with each shot of heroin. Here are effects I have noticed (each of my friends claim to get these same effects):

TOLERANCE
I had gotten up to at least $20 #4 per shot to even feel slight effects from heroin. I was up to about 3-4 shots per day. AS SOON as I starting adding 1mcg naltrexone to my shots I have been catching extreme nods (like never ever before) from $8 of #4 per shot.

Not only has my previous tolerance been obliterated, it does not increase either; if I shoot $8 worth at 10am then another $8 2 hours later the rush is ALL THERE. No decrease in effects with subsequent dosing; each shot is like the first shot of my life no matter how much I've done that day.

CRAVING
Previously shooting junk would almost immediately induce cravings to do more and more and more junk. With naltrexone I experience NO craving to do more heroin at all.

WITHDRAWL
I have yet to experience WD since I've started doing naltrexone with my dope. Yes I have taken enough time off and have felt no signs of WD as well as no cravings when abstinent.

Again this is with doses of 1-2mcg per shot of dope, WITHOUT skipping the naltrexone at all with any of my heroin shots. Even after a week I am still nodding HARD (yes right now in fact) from ~$10 of NE #4.

Feel free tp ask me any q's at all i gott go though i cant keep my eyes open but holy shit i have NEVER nodded this hard from$8 of jj
CretiNation 04:20 13-04-2008
Also the high is a bit different. The rush is full and immediate but the high continues to grow until about 20-30mins when it seems to peak and this is where the serious nodding starts to take place. I will never use chronic opioids without ULD naltrexone again.
johanneschimpo 04:30 13-04-2008
^ Sounds like a damn good example of the placebo effect to me :-)
wiggi 04:41 13-04-2008
^ That sounds entirely too good to be true man.
johanneschimpo 04:45 13-04-2008
The theory is that over time, low-dose naltrexone will lower tolerance, or at least keep it from rising.
Not that it:
increases strength of heroin
makes the rush last for 20-30 minutes instead of 20-30 seconds
eliminate cravings to do more heroin
& prevents withdrawal

This is either total bullshit, or the best damn self-trickery (placebo) I've ever heard of.
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