I don't know how many different pharmaceutical white inks there are, but here is one formulation that I found (in this case used on Clindamycin capsules):
Source: http://www.drugstorepharmacy.ca/medi...d_name_id=4723Opacode White S-1-7085 (pharmaceutical glaze modified, titanium dioxide, isopropyl alcohol, ammonium hydroxide, propylene glycol, n-butyl alcohol and dimethylpolysiloxane).
And this one, from Sigma Cilicaine VK Penicillin Capsules:
Source: http://www.emedical.com.au/default.a...6&itemID=10612Negligible quantities of the following ingredients are present in the white ink used to write the name SIGMA: Pharmaceutical glaze USP/NF, titanium dioxide, isopropyl alcohol, ammonium hydroxide, propylene glycol, butan-1-ol and dimethicone
I'd imagine most white pharamceutical inks are similar in contents...they probably all have titanium dioxide as a major component. It is my guess that since the solvents are evaporated as the ink dries, you are left with the glaze, TiO2, and dimethicone. They are present in such small amounts that I would be surprised if any harm were to come from injection, especially after micro-filtering. I'd like to know a little more about the glaze though!
Results 26 to 50 of 954
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Greenlighter
- Join Date
- Sep 2010
- Posts
- 24
30-09-2010 15:08
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30-09-2010 16:31
the tablets have lemon/lime flavor. the strips have just lime.
james, you are saying they taste exactly the same though?
also, how quickly do hey dissolve in water when prepped for IV? did you have to use heat to expedite?
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30-09-2010 16:44
NVM....looks like you were right, tablets have lemon lime flavor, strips have just lime. Allthough, like I said, they tasted pretty much the exact same to me. They just felt different.
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30-09-2010 18:48
My first question was what's the ba?
Only thing I found in the 3rd link submitted by tchort:
Because of the potentially greater relative bioavailability of SUBOXONE sublingual film compared to SUBOXONE (buprenorphine and naloxone) sublingual tablets, patients switching from SUBOXONE (buprenorphine and naloxone) sub- lingual tablets to SUBOXONE sublingual film should be monitored for over-medication. Those switching from SUBOXONE sublingual film to SUBOXONE (buprenorphine and naloxone) sublingual tablets should be monitored for withdrawal or other indications of under-dosing. In clinical studies, pharmacokinetics of SUBOXONE sublingual film was similar to the respective dosage strengths of SUBOXONE (buprenorphine and naloxone) sublingual tablets, although not all doses and dose combinations met bioequivalence criteria.
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30-09-2010 19:10
awesome! makes total sense, you dont have all that gunk oozing out and you wont swallow as much of it. definetly should have a better BA. with less material they should dissolve much faster too, giving a quicker onset. man, i may just have to switch over.
how long do they take to dissolve when you hit em with water for IV?
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Bluelighter
- Join Date
- Mar 2010
- Posts
- 378
01-10-2010 04:46My Dr was telling me the discount cards are good for six months, there is no plan to release a subutex strip in the forseeable future. I asked if they were getting rid of the pills and she said no, in fact they recommend using the pill formulation for induction, so BA must be pretty close IMO. Im not takng sub now, if I got back on a small doses Id definitely go for the strips due to the ease of cutting them up. I'm not so sure this is the future of meds or just an attempt to provide additional child proofing packaging to appease the DEA. My Dr said only one of her patients were into the strips, because of the $75 coupon, I figured all of them would want to switch, although you'd be srewed if you like to snort your bupe.
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01-10-2010 11:05
I'm really interested in these, I'll post the e-mail and links I got today for everyone in a second.
NSFW:
Questions: When sniffing something does it have to be in the nostrils, or are the membranes further back. Because it would be easy to put the strip in your nose, and it would dissolve, but if it had to be far back it might cause a problem.
This seems great for IV, I haven't looked at all the ingredients, but so far this is looking promising, I might ask to switch if I can still sniff.
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01-10-2010 15:59
i wonder if you could put them on a wet band aid on your balls. i kid, i kid.
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01-10-2010 18:45
I think it would be simpler to make liquid nasal spray solution out of the strips in order to administer them intranasally. I think this would also be much easier on your nostrils membranes, as well as your lungs.....becuase the drug will be dissolved inside a liquid, therefore it is less likely to float through the air and end up in your lungs, and more likely to stay inside the water, stuck to your noses membranes. Allthough, sticking the strip in your nose may work a well, but I think making a "nasal spray" solution would be more efficient. Just make sure you use anti-bacterial water.
Also....yes, the strips do work well for IV. They have MUCH less fillers and binders in them to worry about. Allthough that shouldnt be much of an issue if you use a micron filter like you should. But for most of us who dont have easy access to micron filters, these strips may prove to be a much healthier alternative to the "talc filled" pills.
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01-10-2010 19:31
ive been on sub for a long time. i have a fairly simple question. i dislike the buzz from sub so i snort a very small amount in the am and before bed, just enuff to kill the wd's. one pill will last me around a week. since these come in sealed packs will they degrade or dissolve once they are open.
if i take the same dose and have the strip out of the pack for a week will it lose potency or will i have any other problems. i was told they degrade once open. i didnt know if it was true or b/s.
thanks
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01-10-2010 19:47
They more than likely degrade much quicker than the tablets would because there is MUCH less fillers and binders to protect the active chemicals from the elements. The strips dont really have much protecting them from heat, moisture, light, etc....so it would be best to try to "seal" them up in something else(or even back in the same package) in order to prevent any decomp. They were made to be used all at once so I doubt there are any "preservatives" in place to help prevent decompostion once opened.
Just do your best to keep them away from the elements and im sure you will not notice any degredation in the quality of the suboxone.
Since these strips are so new, only time will tell how well they do outside of there packaging for relatively long periods of time.
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Bluelighter
- Join Date
- Mar 2009
- Posts
- 101
02-10-2010 05:27So do you all think they ARE safe to shoot?
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Greenlighter
- Join Date
- Oct 2010
- Posts
- 1
02-10-2010 06:16No they are not safe to shoot because they contain Naloxone so if you shoot them it will send you in to full withdrawl. Any body who has a sub film perscription ask your doctor for the 75$ off card or print it on the suboxone website. it will be much cheaper.Also, you can cut the 8mg strips into pieces and they last and still work just fine.
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02-10-2010 06:23
HAHHA...thr nalaxone doesnt do ANYTHING. You CAN Inject these strips just like you can inject the pills. Ive been injecting the pills 3 times a day for months now and not once have I gone into withdrawals. In fact, it ives me a euphoric rush. I think you need to do some reading about suboxone on BL before you start making posts like that. Im not trying to be rude but that is just blatantantly false.
There are MANY MANY people on this website that inject there suboxone on a daily basis, which proves what you are saying wrong. I really am not trying to be rude here its jsut that I can tell by what you said that you have done VERY LITTLE research on whether or not that statement you made is true or false.....and I think its important before you post, to make sure what your saying makes sense, as to not spread false information, especially through the BL community, which is full of people looking for answers to questions, and they expect those answers to be truthfull.Last edited by jamesBrown; 02-10-2010 at 06:35.
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Greenlighter
- Join Date
- Oct 2010
- Location
- around the sun
- Posts
- 28
02-10-2010 06:57I'm Rather stoked I am on subutex I really feel bad for you guys with these films they prolly gonnan suck anyway./.. GEt on subutex if you can its cheaper and better all around wont make you sick or depressed like Suboxone does cuz of shitty Naloxone
Good luck to everyone
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02-10-2010 07:08
Actually, the suboxone gives me euphoria, energy, and acts as an anti-depressant......i am more than happy taking my suboxone. Of course I dont take it as prescribed. I only take 0.5mg doses so that bupernorphines full agonist metabolite norbupernorphine can bind to my brains open receptors and give me all these euphoric and beneficial effects. the nalaxone is comletely inactive and i have never had any problems with it.
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02-10-2010 13:55
dont you mean euphorical effects? haha, sorry, couldnt help it.
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03-10-2010 00:34
yeah naloxone does suck ass, but its really not that noticeable with suboxone. sometimes if you take too much you do get a headache. wow, im fucked up.
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Bluelighter
- Join Date
- Mar 2006
- Posts
- 52
05-10-2010 23:10I just switched to the strips yesterday after seeing my doctor. The topic of the new formulation film was brought up almost immediately, and I was given a choice to try them out. Including the $75 discount card and no insurance I paid ~$35 for 10 strips. I found them to dissolve in about 1/4 of the time it takes for me when taking suboxone tablets, less than 5 minutes. To my disappointment the film was exactly the same taste as the tablets. Either way I was much happier; it look a lot less time to dose and created hardly ANY residual "fluid" in ones mouth as the tablets do. I do not, in my experience, feel that the BA for the film is really much higher than the tablets. Hope this helps
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05-10-2010 23:58
im glad that you are happy about switch to the strips. And I know exactly what you are talking about with the whole having a shitload of saliva in your mouth from letting the tablets dissolve. Allthough, I found that if I crushed the pill up before I put it under my tounge, it would dissolve extremely quickly, and that would be much less of an issue.
As far as the bioavailability goes......im pretty sure the strips for some reason actually DO have a slightly higher BA, but since most people are taking such high doses of suboxone, any increase in the BA wouldnt result in you noticing any different effect from the drug. Just like taking more and more sub than your prescribed dose will not increase the effects.
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Bluelighter
- Join Date
- Mar 2010
- Location
- Minneapolis, Middlewest
- Posts
- 251
06-10-2010 00:23My doc gave me the exact same thing. The $75 discount card! Haha!
Here's my reaction to the strips:
As some of you may know, I've been binging on H for a good two months, going on two and a half. So as I talk myself into going back on Subs I think, "and this time I have the strips!"
It becomes fairly apparent that the strips are far more convenient than anything. It takes them about one minute to fully dissolve (if I've taken a sip of water beforehand) and after that I leave them in there for about the same amount of time as I would with the pills (5-10 minutes), to make sure that I get it all absorbed. I was still feeling like shit despite taking around 8mgs over a four hour period, so I decided to booty-bang (rectal ROA) another 4mgs. When I prepared the strips in my modified syringe, it would seem that they didn't want to dissolve as quickly as they did in my mouth. It took a full 10 minutes before they were dissolved enough to administer. I don't know if a whole lot of bupe even ended up in the water in my modified rig.
I used to snort my bupe occasionally, which is kind of a downer with these new strips. I didn't really do it enough to the point where I'm really disappointed with the strips. Overall it seems that the strips are simply a matter of convenience for people who choose to use the sublingual ROA. They certainly do trump the tablets in that respect, and I do notice a slight difference in the "feel" of 2mg sublingually on the films vs 2mg sublingually with the pills. The bioavailability does feel higher. However, I think if the cost of the strips isn't equal to the cost of the pills after I use up my discount, I'll probably just go back to the pills as a matter of cost.
And oh yes. . . the flavor is exactly the same, to those who've been discussing and bickering about it. The only thing a little different is the after taste, which is slightly 'chemical.'
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